In certain cases, frequent use of high-THC cannabis has been associated with health risks such as increased risk of psychosis, respiratory symptoms, and adverse effects on adolescent brain development. A recent study found that rates of cannabis-related hospitalizations associated with mental or behavioural disorders doubled from 2.11 to 5.18 per 100 000 between 2006 and 2015. Young people aged 15 to 24 years represented the greatest proportion of any age group. Of special note, psychosis was associated with almost half of all cannabis-related hospitalizations in 2015.